RNA interference for wheat functional gene analysis

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RNA interference-based gene silencing as an efficient tool for functional genomics in hexaploid bread wheat.

Insertional mutagenesis and gene silencing are efficient tools for the determination of gene function. In contrast to gain- or loss-of-function approaches, RNA interference (RNAi)-induced gene silencing can possibly silence multigene families and homoeologous genes in polyploids. This is of great importance for functional studies in hexaploid wheat (Triticum aestivum), where most of the genes a...

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Genome Analysis RNA Interference-Based Gene Silencing as an Efficient Tool for Functional Genomics in Hexaploid Bread Wheat

Insertional mutagenesis and gene silencing are efficient tools for the determination of gene function. In contrast to gainor lossof-function approaches, RNA interference (RNAi)-induced gene silencing can possibly silence multigene families and homoeologous genes in polyploids. This is of great importance for functional studies in hexaploid wheat (Triticum aestivum), where most of the genes are ...

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Rna Interference: Tool for Gene Silencing

Over the past two decades, dramatic advances in the role of RNA in normal health and disease have been greatly expanded. During development Small RNA molecules regulate eukaryotic gene expression and also during responses to stress including viral infection. RNA interference (RNAi) is a highly conserved process in eukaryotes that leads to post-transcriptional gene silencing through degradation ...

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Functional genomic analysis of RNA interference in C. elegans.

RNA interference (RNAi) of target genes is triggered by double-stranded RNAs (dsRNAs) processed by conserved nucleases and accessory factors. To identify the genetic components required for RNAi, we performed a genome-wide screen using an engineered RNAi sensor strain of Caenorhabditis elegans. The RNAi screen identified 90 genes. These included Piwi/PAZ proteins, DEAH helicases, RNA binding/pr...

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ژورنال

عنوان ژورنال: Transgenic Research

سال: 2007

ISSN: 0962-8819,1573-9368

DOI: 10.1007/s11248-007-9150-7